Research Initiatives

  • (2016-2018) Two-year award from the Queenscare Foundation to address the current challenges and opportunities to deliver high-efficiency cancer care and improve access to AYA specific cancer care for Los Angles county hospital patients

  • (2016-2018) Two-year award from the UniHealth Foundation to evaluate the efficiencies and effectiveness of AYA program, transferability and sustainability.

  • (2013-2015) Two-year award from the UniHealth Foundation to develop and implement a multi-disciplinary, collaborative care model that addresses the unique clinical needs of the AYA population in Los Angeles.

  • (2013) Concern Foundation is funding the development of our AYA Patient Clinical and Bio-Informatics Database. This key infrastructural element will work concordant with the numerous efforts across the Norris Comprehensive Cancer Center and Hospital, while allowing us to collect patient data to drive our research aims.

  • (2012) LIFE Cancer Survivorship Database for Pediatric Cancer is being led by Dr. David R. Freyer. The purpose of this study is to develop a mechanism for utilizing the comprehensive clinical database of childhood cancer survivors at Children’s Hospital Los Angeles (CHLA) for research purposes. Using clinical information obtained from follow-up visits of childhood cancer survivors, the database will focus on interventions to improve health status and health-related quality of life in childhood cancer survivors. This study is currently recruiting participants.

  • (2012-2014) The Children’s Oncology Group (COG) and the Aflac Foundation awards outstanding investigators early in their careers who are interested in adolescent and young adult oncology research. Dr. Melanie Goldfarb received this award in 2012 with mentorship by Dr. Stuart Siegel and Dr. David R. Freyer.

  • (2012) Concern Foundation is funding the development of an AYA Tissue Sample and Bio-Repository with more than 40 years of Los Angeles County patient and tissue sample data. As part of the Los Angeles Residual Tissue Repository (LA-RTR) at USC Norris Comprehensive Cancer Center, Dr. Wendy Cozen is using this very unique resource to advance our related research efforts.

  • (2012) St. Baldrick’s Foundation has provided grant support to Dr. Dennis Deapen and Dr. Myles Cockburn from USC’s Los Angeles Cancer Surveillance Program (CSP) to analyze cancer-specific incidence and mortality trends for the Los Angeles County AYA population for period 1975 – 2010. This is a landmark study that will provide us with a foundational understanding of cancers in the AYA population serving as a foundation both here in Los Angeles and nationwide.

  • (2012) Aflac Foundation is funding a quality of life study led by Kathleen Meeske, Ph.D. on the “Psychosocial Outcomes in Adolescent Cancer Survivors During Their First Five Years of Survivorship: A Longitudinal Study”

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Published Papers

  • Adolescent and Young Adult Oncology Training for Health, A Position Statement (2010). Hayes-Lattin B, et al. Read More →

  • Adolescent and Young Adult Oncology, An Emerging Subspecialty (2012). Williams KA. Read More →

  • Assessing information and service needs of young adults with cancer at a single institution the importance of information on cancer diagnosis, fertility preservation, diet, and exercise (2013). Gupta AA, et al. Read More →

  • Cancer survivorship practices, services, and delivery. A report from the Children’s Oncology Group nursing discipline (2011). Eshelman-Kent D, et al. Read More →

  • Children, adolescents, and young adults with leukemia the empty half of the glass is growing (2012). Bleyer A, Siegel SE, Coccia PF, Stock W, Seibel NL. Read More →

  • Childrens Oncology Groups 2013 Blueprint for Research Adolescent and Young Adult Oncology (2013). Freyer, DR, et al. Read More →

  • Clinical trial participation and time to treatment among adolescents and young adults with cancer does age at diagnosis or insurance make a difference (2011). Parsons HM, et al. Read More →

  • Cryptorchidism and testicular germ cell tumors comprehensive meta-analysis reveals that association between these conditions diminished over time and is modified by clinical characteristics (2013). Banks K, et al. Read More →

  • Examination of the Increase in Thyroid Cancer Incidence Among Younger Women in the United States by Age, Race, Geography, and Tumor Size, 1999 2007 (2011). Holman D, et al. Read More →

  • Fecal microbiota diversity in survivors of adolescent young adult Hodgkin lymphoma a study of twins (2013). Cozen W, et al. Read More →

  • Heterogenous effect of androgen receptor CAG tract length on testicular germ cell tumor risk, shorter repeats associated with seminoma but not other histologic types (2011). Davis-Dao CA, et al. Read More →

  • Improved survival for children and adolescents with acute lymphoblastic leukemia between 1990 and 2005 a report from the children’s oncology group (2011). Hunger SP, et al. Read More →

  • Latest Estimates of Survival Rates of the 24 Most Common Cancers in Adolescent and Young Adult Americans (2011). Bleyer, A. Read More →

  • Loren et al. Fertility Preservation for Patients with Cancer. American Society of Clinical Oncology Clinical Pactice Guideline Update. Read More →

  • Measures And Methods For Symptom And Symptom Cluster Assessment In Adolescents And Young Adults With Cancer. Read More →

  • Meta-analysis identifies four new loci associated with testicular germ cell tumor (2013). Chung CC, et al. Read More →

  • No difference in outcome between children and adolescents transplanted for acute lymphoblastic leukemia in second remission (2011). Dini G, et al. Read More →

  • Population-based case-control study of recreational drug use and testis cancer risk confirms an association between marijuana use and nonseminoma risk (2012). Lacson, J, et al. Read More →

  • Reducing the Long-term Effects of Chemotherapy in Young Women With Early-Stage Breast Cancer (2011). Hope S, et al. Read More →

  • Rethinking Adherence A Proposal for a New Approach to Risk Assessment (2012). Rosenberg AR, et al. Read More →

  • Shorter Androgen Receptor CAG Repeat Lengths Associated with Cryptorchidism Risk among Hispanic White Boys (2012). Davis-Dao C, et al. Read More →

  • Talking About Cancer and Meeting Peer Survivors Social Information Needs of Adolescents and Young Adults Diagnosed with Cancer (2012). Kent EE, et al. Read More →

  • The Adolescence of Young Adult Oncology (2009). Albritton K, et al. Read More →

  • The Clinical Trials Gap for Adolescents and Young Adults with Cancer. David R. Freyer, Nita L. Seibel. Read More →

  • Teenage and Young Adult Cancer Related Fatigue. Anna Spathis, Sara Booth, Sarah Grove, MB BChir, Helen Hatcher, Isla Kuhn, Stephen Barclay. Read More →